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Pathology Liver & Biliary Tract 74438d0d

Amebic liver disease is characterized by?

A
Most common in right lobe of the liver
B
Diarrhea is the most common presentation
C
Resistant to metronidazole
D
Liver is the most common primary site of infection
High-Yield Explanation
Ans is 'a' i.e., Most common in right lobe of the liver Amoebic liver disease* Amoebic liver abscess is the most common extra intestinal manifestation ofamoebiasis (primary site of infection is intestine).* Most common in postero-superior surface of the right lobe. Usually there is one large solitary abscess.* The necrotic contents of liver abscess are classically described as anchovy-sauce pus.* Although colon is the primary site of infection, diarrhea is not that common.* Common clinical features are right upper quadrant pain, fever, weight loos and hepatomegaly.* Pleuropulmonary involvement is the most frequent complication of amoebic liver abscess.* Erythrophagocytosis is seen amebiasis.* Metronidazole is the drug of choice. Response is dramatic.

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