The renal biopsy of a 6-year-old boy with recurrent gross hematuria shows IgA nephropathy. The urinary protein excretion is 130 mg/day. Which of the following is the most appropriate next step in the management -

Ans. is 'a' i.e., Administer coicosteroids T/T of IgA nephropathy ? o There is no proven t/t for IgA nephropathy. o The primary t/t is proper blood pressure control. The drugs which have been proved useful are :? i) Fish oil (It contains omega - 3 fatty acids). It is an antiinflammatory agent and it prevents the rate of renal progression. ii) Immunosuppressive therapy - It is done with coicosteroids with or without cytotoxic therapy. iii) ACE inhibitors and Angiotensin II receptor antagonists - Their role in reducing proteinuria and retarding the rate of renal progression is still to be determined. iv) Prophylactic antibiotics and tonsillectomy - It may reduce frequency of gross hematuria but they have no effect on progression of renal disease.