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Medicine Blood Bank & Transfusion Therapy 73ca1dfb

Acute renal failure in a patient who received incompatible blood transfusion with hemolytic reaction is best managed by:

A
20% Mannitol
B
IV fluids with K+ supplementation
C
Alkalinizing the urine
D
Stopping blood transfusion
High-Yield Explanation
Microvascular thrombosis and deposition of haemoglobinin the distal renal tubule can result in acute renal failure. The extent of precipitation is inversely related to urine flow.I.V. fluids, vasopressors and diuretics should be given to maintain renal perfusion pressure, and to produce a diuresis. If acute renal failure develops, hemofiltration should be considered.

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