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Pharmacology General 739efbef

Spironolactone is contraindicated with which of the following drugs:

A
Enalapril.
B
Atenolol.
C
Verapamil.
D
Chlorthiazide.
High-Yield Explanation
Spironolactone is a K+ sparing diuretic. It should be used cautiously if the patient is receiving K+ salts or drugs increasing serum K+ levels. ACE inhibitors can also cause hyperkalemia as an adverse effect. If these are combined with K+ sparing diuretics, cardiac arrhythmia due to high serum K+ levels may develop

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