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Pathology Thyroid Tumor 7366dbdb

RET proto-oncogene is associated with:-

A
Medullary thyroid cancer
B
Paraganglioma
C
Papillary thyroid cancer
D
CNS tumors
High-Yield Explanation
RET proto-oncogene: Associated with development of MEN II syndrome (affects thyroid & adrenal medulla) Therefore, patients have risk of developing medullary thyroid cancer & pheochromocytoma. Thyroid tumors & associated mutations: - Papillary thyroid cancer: RET-PTC gene - Follicular thyroid cancer: RAS gene - Anaplastic thyroid cancer: p53 gene

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