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Pharmacology Endocrinology 7342c21d

The physical half life of radioactive iodine 131 is

A
8 hours
B
8 days
C
16 days
D
60 days
High-Yield Explanation
RADIOACTIVE IODINE The stable isotope of iodine is 127I. Its radioactive isotope of medicinal impoance is: 131I physical half-life of iodine 131 is 8 days. Mech of action:- 131I emits X-rays as well as b paicles. latter are utilized for their destructive effect on thyroid cells. 131I is concentrated by thyroid, incorporated in colloid--emits radiation from within the follicles. The b paicles penetrate only 0.5-2 mm of tissue. The thyroid follicular cells are affected from within, undergo pyknosis and necrosis followed by fibrosis when a sufficiently large dose has been administered, without damage to neighbouring tissues. Ref:- kd tripathi; pg num:-255

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