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Microbiology General 732ed024

What is true about Histoplasmosis -

A
In early stage it is indistinguishable from TB
B
Culture is not diagnostic
C
Mycelial forms are infectious form
D
Person to person spread occurs by droplet infection
High-Yield Explanation
Chronic cavitary histoplasmosis is seen in smokers who have structural lung disease (e.g. bullous emphysema) is characterized upper-lobe infiltrates, cavitation, and pleural thickening- mimics cavitary tuberculosis. Isolation of fungi by culture and demonstration of dimorphism is diagnostic. Reservoir of infection: Soil Microconidia (spores) are the infective form and mode of infection is inhalation. Person to person or animal to man transmission in not known so far for Histoplasmosis.

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