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Medicine Haematology 73267051

In which leukemia, autoimmune hemolytic anemia is most common -

A
ALL
B
AML
C
CML
D
CLL
High-Yield Explanation
<p>Autoimmune hemolytic anemia may occur as a complication of chronic lymphocytic leukemia.About 20% of cases of CLL develop a coomb&;s positive autoimmune hemolytic anemia.This is due to the presence of warm antibodies (Ig G) that coat RBC&;s that are reactive at room temperature .Red cells coated with Ig G along with C3 on its surface fuher promote red cell-leucocyte interaction ,accounting for more severe hemolysis.</p><p>Harsh mohan textbook of pathology sixth edition pg no 312.</p>

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