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Pharmacology All India exam 7301c2e6

Which of the following used as preanesthetic medication causes longest amnesia?

A
Midazolam
B
Diazepam
C
Lorazepam
D
Flunitrazepam
High-Yield Explanation
The longest amnesia is produced by lorazepam although half-life of lorazepam (15 hours) is shoer than diazepam (36 hours) and this is probably because of its strong receptor binding potential. Its relatively potent amnesic effect, with its anxiolytic and sedative effects, makes lorazepam useful as premedication.

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