Cat scratch disease is -

Ans. is 'c' i.e., Associated with a pathognomonic histological picture Cat scratch disease (CSD) . Caused by Baonella henselae --) a gram negative bacteria. . Domestic cat is the animal reservoir . The flea acts as a vector in the cross-infection of cats, but its role in human infection is not clear. . Man is infected by a cat scratch . Clinical manifestations - Localized papule, pustule - Tender regional lymphadenopathy - Systemic symptoms -3 malaise, anorexia and weight loss - No fever - Encephalitis, meningitis, seizures, transverse myelitis - Granulomatous hepatitis, splenitis, osteomyelitis - Perinaud's oculoglandular syndrome. Pathology - The histopathologic hallmark of CSD is granulomatous inflammation with stellate necrosis but no evidence of angiogenesis. - Biopsy samples stained with wahin-starry silver. Remember Infection with B. henselae produces two entirely different pathologic reaction, depending on the immune status of the host : Granulomatous inflammation --> Cat scratch disease Angiogenesis --> Bacillary angiomatosis