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Pharmacology FMGE 2019 72e57a54

Monoclonal antibody used in cancer is

A
Rituximab
B
Cisplatin
C
5-fluorouracil
D
Methotrexate.
High-Yield Explanation
Rituximab is a monoclonal antibody against CD20. It is used for treatment of: - Non-Hodgkin lymphoma Chronic lymphoid leukemia Rheumatoid ahritis SLE Auto-immune hemolytic anemia Idiopathic thrombocytopenic purpura OTHER OPTION: Cisplatin is most emetogenic anticancer drug - DOC- esophageal or gastric cancer 5-fluorouracil is a pyrimidine analog and inhibit DNA synthesis by competing with DNA polymerase. Methotrexate is a dihydro folic acid reductase inhibitor. It decreases the formation of DNA.

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