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Pathology Plasma Cell Disorders and Multiple myeloma 72bebbb3

Which of the following is false about monoclonal gammopathy of unknown significance (MGUS)?

A
Less than 3g/dL of monoclonal protein
B
No evidence of Bence-Jones proteinuria
C
Bone marrow plasma cells less than 10%
D
Does not progress to multiple myeloma
High-Yield Explanation
MGUS: MGUS is the most common plasma cell disorder Asymptomatic BM Plasma Cells < 10% S. Para Protiens < 3g/dl 3% of MGUS ( aged > 50yr) can develop Multiple myeloma. 5% Of MGUS (aged >70yr) can develop multiple myeloma. Approximately 1% of patients with MGUS develop a symptomatic plasma cell neoplasm, usually multiple myeloma, per year.

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