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Physiology General 724faeea

Which of the following factor increases gastric motility?

A
Acid in duodenum
B
Fatty food in stomach
C
Carbohydrate in stomach
D
None of the above
High-Yield Explanation
Fats, carbohydrates, and acid in the duodenum inhibit gastric acid and pepsin secretion and gastric motility neural and hormonal mechanisms. The messenger involved is probably peptide YY. CCK has also been implicated as an inhibitor of gastric emptying. Hyperosmolality of the duodenal contents is sensed by "duodenal osmoreceptors" that initiate a decrease in gastric emptying, which is probably neural in origin. Ref: Barrett K.E., Barman S.M., Boitano S., Brooks H.L. (2012). Chapter 27. Gastrointestinal Motility. In K.E. Barrett, S.M. Barman, S. Boitano, H.L. Brooks (Eds), Ganong's Review of Medical Physiology, 24e.

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