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Pharmacology Sex-Hormone 720fe8e8

All are true about estrogen EXCEPT:

A
Causes cholestasis
B
Used in treatment of gynecomastia
C
Used in HRT
D
Increased risk of breast cancer
High-Yield Explanation
ANSWER: (B) Used in treatment of gynecomastiaREF: Harrison's 18th ed chapter 346, KDT 3d1 edition page 276Estrogen receptor antagonists are used in the treatment of gynecomastia not estrogenAdverse effects of Estrogen:Suppression of libido and gynecomastiaFusion of epiphysesEndometrial carcinomaIncreased incidence of breast cancerIncreased incidence of cholestasis and gall stonesIncreased chances of thromboembolism

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