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Pathology AIIMS 2018 71f6de26

Immunofluorescence staining pattern from a kidney biopsy from a 35-year-old patient presenting with proteinuria has been shown below. What is the most probable cause?

A
FSGS
B
PSGN
C
Lupus Nephritis
D
Goodpasture syndrome
High-Yield Explanation
FSGS- Focal segmental glomerulosclerosis is associated with focal involvement of kidneys and deposition of IgM,C3 ,C1q PSGN- It is an immunocomplex disease and granular pattern is observed on immunofluorescence. There is deposition of C3,C1q and IgG in granular pattern Goodpasture syndrome- Auto antibodies against basement membrane ,linear pattern on immunofluorescence Lupus Nephritis- seen in SLE.

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