Half-life of factor VIII

Factor VIII (8) Dosage Calculated on the basis that 1 unit/kg of factor VIII leads to a rise in plasma factor VIII of approximately 2%. EXAMPLE: 50 units/kg will increase factor VIII level by ~100%. Doses are rounded UP to the nearest l size. The half-life of factor VIII is 8-12 hours. Refer also to RCH Clinical Practice Guideline Haemophilia.