A 72-year-old woman presented with skin changes over her left breast. She had a history of breast cancer 5 years earlier and was treated with a lumpectomy and radiation therapy. What is the diagnosis?

Answer C. Radiation-induced angiosarcomaThe correct answer is radiation-induced angiosarcoma. This is a rare complication following treatment for breast cancer. Patients may present with asymptomatic skin changes which may be difficult to differentiate from radiation-induced changes. Surgical management involving a mastectomy is the standard of care.