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Physiology Endocrinology 70e4345a

Aldosterone receptors are present in all except

A
Liver
B
Colon
C
Hippocampus
D
Distal nephron
High-Yield Explanation
The mineralocoicoid receptor (or MR, MLR, MCR), also known as the aldosterone receptor or nuclear receptor subfamily 3, is a receptor with equal affinity for mineralocoicoids and glucocoicoids.mineralocoicoid receptor is expressed in many tissues, such as the kidney, colon, hea, central nervous system (hippocampus), brown adipose tissue and sweat glands. In epithelial tissues, its activation leads to the expression of proteins regulating ionic and water transpos(mainly the epithelial sodium channel or ENaC, Na+/K+ pump, serum and glucocoicoid-induced kinase or SGK1) resulting in the reabsorption of sodium, and as a consequence an increase in extracellular volume, increase in blood pressure, and an excretion of potassium to maintain a normal salt concentration in the body.Ref: Ganong&;s review of medical physiology;24th edition; page no-364

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