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Medicine General 70adc6a2

A doctor was accidentally exposed to HIV by a needle stick injury while sampling HIV positive patient. A drug prescribed to him would be -

A
Zidovudine + Lamivudine + Indinavir for 4 weeks
B
Zidovudine + Lamivudine + Navirapine for 4 weeks
C
Zidovudine + Stavudine for 4 weeks
D
Zidovudine + Lamivudine for 4 weeks
High-Yield Explanation
Needlestick injury is the most common cause of HIV infection among health care workers. The guidelines for post-exposure prophylaxis of HIV are A) For routine exposures a combination of two nucleoside reverse transcriptase inhibitors for 4 weeks. B) For high risk or complicated exposures a combination of two nucleoside reverse transcriptase inhibitors plus a protease inhibitor for 4 weeks. Inspite of the guidelines regimen B is given for all types of exposure Thus the treatment is obvious in this doctor. Also Remember Examples of Nucleoside reverse transcriptase inhibitors Zidovudine Lamivudine Stavudine Didanosine Zalcitabine A bacavir Protease inhibitors Saquinavir Indinavir Ritonavir NelfinavirAmprenavir

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