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Pharmacology General 709a8e8c

Treatment of choice in a patient of acute pulmonary embolism with right ventricular hypokinesis and compromised cardiac output but normal blood pressure is:

A
Thrombolytic agent
B
Low molecular weight heparin
C
Warfarin
D
IV filters
High-Yield Explanation
Successful fibrinolytic therapy rapidly reverses right hea failure. Thrombolytic therapy in pulmonary embolism is used for patients who present with hemodynamic compromise, patients who develop hemodynamic compromise during conventional therapy with heparin, and patients with embolism associated with intracavitary right-hea thrombi. Acute embolectomy might be considered in patients with hemodynamically massive PE or right-hea thrombus who have an absolute contraindication to anticoagulant or thrombolytic therapy. Ref: Fedullo P.F. (2011). Chapter 72. Pulmonary Embolism. In V. Fuster, R.A. Walsh, R.A. Harrington (Eds), Hurst's The Hea, 13e.

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