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Pharmacology General 7010d5ab

Following are the propeies of Biguanides, EXCEPT:

A
Decrease hepatic gluconeogenesis
B
Not contraindicated in renal dysfunction
C
Can be used along with sulfonylureas
D
Don't stimulate insulin Release
High-Yield Explanation
Biguanides are contraindicated in patients with renal failure, congestive hea failure, alcoholism and hepatic diseases. Ref: Richard Finkel, Michelle Alexia Clark, Pamela C. Champe, Luigi X. Cubeddu (2009), Pharmacology, 4th Edition, Lippincott Williams and Wilkins Publications, United States Page 292

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