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Pharmacology General 6fbdc56a

Which of the following drug is an inverse agonist at H3 receptors used for Narcolepsy?

A
Dexmedetomidine
B
Pitolisant
C
Icatibont
D
Secukinumab
High-Yield Explanation
Pitolisant (Tiprolisant) is a inverse agonist of H3 receptors approved for Narcolepsy. H3 receptors are presynaptic receptors and inverse agonist will lead to increased histamine release and promote wakefulness.

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