Methotrexate toxicity is prevented by giving?
High-Yield Explanation
Ans. is 'b' i.e., Folinic acid * Folinic acidFor preventing methotrexate toxicity* AllopurinolTo prevent hyperuricemia caused by rapid destruction of cells during cancer chemotherapy.* Lithium carbonateIt has stimulant effect on bone marrow, so used during myelosuppresive drug therapy.* OndensetronFor controlling cytotoxic drug induced vomiting.* MesnaFor prevention of cyclophosphamide/ formamide indused hemorrhagic cystitis