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General Medicine General 6f748e5c

A 63-year old man presented with massive splenomegaly, lymphadenopathy and a total leucocyte count of 17000 per mm3. The flow cytometery showed CD 19 +, CD5 +, CD23 -, monoclonal B-cells with bright kappa positively comprising 80% of the peripheral blood lymphoid cells. Which of the following is the most likely diagnosis?

A
Mantle cell lymphoma
B
Follicular lymphoma
C
Hairy cell leukemia
D
Splenic lymphoma with villous lymphocytes

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