Radiology General 6f28010e Hallmark of breast malignancy on mammography : A Low density lesion B Smooth margin C Clusters of micro calcification D Popcorn calcification High-Yield Explanation Microcalcification's is pathognomonic sign for breast carcinoma. It may be seen in 30% cases of invasive carcinoma and 95% of cases of DCIS (granular and casting).