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Pharmacology General 6f0fd48f

Benzodiazepine binding ste on GABA receptors is on ?

A
y-subunit
B
a-subunit
C
b-subunit
D
d-subunit
High-Yield Explanation
Ans. is'b'i.e., a-subunitThe exact subunit structures of native GABA receptors are still are unknown, but it is thought that most GABA receptor are composed of alpha, beta & gamma subunits that Coassemble with some unceain stoichiometry.Binding site of GABA is on beta-subunit.Benzodiazepine site is located on the a subunit but the stabilization or completion of that site in the assembled. Structure also requires the y subunit.

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