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Surgery General 6ee3f046

Fever in burnt patient is caused by:a) Due to hypermetabolismb) Toxin released by dead tissuec) Infectiond) Dead tissue products

A
a
B
ac
C
ad
D
b
High-Yield Explanation
Long: Principles and Practice of Pediatric Infectious Diseases, (3rd ed chapter 91) writes- "Diagnosis of infectious complications in a burn victim is challenging. Although fever and elevated peripheral white blood cell count with a left shift are usual indicators of infection, their positive predictive value for diagnosis of infectious complications in burn victims is very low because they are commonly seen in uninfected burned children whose wounds are uncovered. Neither severity of fever (frequently > 39°C) nor response to antipyretic therapy is a reliable indicator of infection. Peak fever in burned children without infection usually occurs on the second day after the burn, with a second peak around the sixth and seventh days. Fever is probably the result of an increase in metabolic rate and an alteration of hypothalamic temperature regulation. Fever usually subsides without specific therapy, coincident with re-epithelialization of the burn wound or successful grafting of all open areas. Thus, fever alone in the burned child is not a reliable indicator of infection or of the need to investigate for infection or prescribe antibiotic therapy."

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