All the following are true of the active site of enzymes, except

Active site is a 3D cleft formed by groups that come from different pas of amino acid sequence. 2 PAS: CATALYTIC SITE and BINDING SITE Active sites are clefts 3Dimensional Site is contributed by Amino acids far apa in the enzyme Amino acids are arranged precisely-only specific substrate can bind. Serine, His, asp, glu, cys make up the active site Substrates are bound to enzymes by multiple weak attraction Ref: KD Tripathi 8th ed.