Full 2L QBank
Anatomy General anatomy 6ec0c054

Which of the following statement best describes the mechanism of action of insulin on target cells

A
Insulin binds to cytoplasmic receptor molecule and is transferred as a hormone receptor complex to the nucleus where it acts to modulate gene expression.
B
Insulin binds to a receptor molecule on the outer suace of the plasma membrane and the hormone receptor complex activates adenylate cyclasel through the Gs protein.
C
Insulin binds to a transmembrane receptor at the which outer suace of the plasma membrane, activates the tyrosine kinase that is the cytosolic domain of the receptor.
D
Insulin enters the cell and causes the release ofcalcium ions from intracellular stores.
High-Yield Explanation
Ref-Goodman and Gilman 12/e p1241) Enzymatic Receptors have two sites, the drug binds on the extracellular site and the intracellular site has enaymatic activity (mostly tyrosine kinase) This enzyme can be activated AK-STAT pathway. Insulin, growthormone, prolactin and cvtokines act enrvmatic receptors.
← Previous Question Next Question →

Related Anatomy MCQs

Major supply of medial surface of cerebral hemisphere
General
All of the following organs are in direct contact with the spleen except?
General
What structure passes through the quandrangular space ?
General
Midpoint between suprasternal notch and pubic symphyses passes through which plane?
General
Kilian's dehiscence is outpouclμng of:
General
Explore All Anatomy Questions →

Practice 2,00,000+ NEET PG Questions Free

Timed mock tests, mistake queue analytics, audio lectures & zero attempt limits on i❤️Exams.

Start Free Mock Test Now