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Pharmacology Kidney 6e940be2

Thiazide diuretics can be used for the treatment of all of these conditions EXCEPT

A
Idiopathic hypercalciuria with nephrocalcinosis
B
Hyperlipidemia
C
Congestive Hea Failure
D
Hypeension
High-Yield Explanation
Thiazides cause hyperlipidemia as adverse effect and thus cannot be used to treat this condition. Indications of thiazides: Diuretic Uses: Non-diuretic Uses: Hypeension (First line drugs) Congestive hea failure Diabetes insipidus Idiopathic hypercalciurea with Nephrocalcinosis Loop diuretics cause hypocalcemia by increasing the excretion of Ca2+ whereas thiazides cause hypercalcemia by decreasing its excretion. Thiazides reduce the excretion of Ca++ in the kidney, so can be used for the treatment of patients with hypercalciuria and recurrent Ca++ stones in the kidney.

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