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Anaesthesia General anaesthesia 6e5f7d29

The anaesthetic agent that causes maximum increase in intracranial pressure is

A
Isoflurane
B
Halothane
C
Enflurane
D
Desflurane
High-Yield Explanation
By dilating cerebral vessels, halothane lowers cerebral vascular resistance and increases cerebral blood volume and CBF. Autoregulation, the maintenance of constant CBF during changes in aerial blood pressure, is blunted. Concomitant rises in intracranial pressure can be prevented by establishing hyperventilation before the administration of halothane. Cerebral activity is decreased, leading to electroencephalographic slowing and modest reductions in metabolic oxygen requirements. Ref: Miller's anesthesia 8th edition Ref: Morgan & Mikhail's clinical anesthesiology 6e

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