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Microbiology Immunology 6e43d202

Synthesis of an immunoglobulin in membrane bound or secretory form is determined by:

A
One turn to two turn joining rule
B
Class switching
C
Differential RNA processing
D
Allelic exclusion
High-Yield Explanation
Ans. is 'c' i.e., Differential RNA processing (Ref: Kuby Immunolo 6th/e, p. 130 - 131)* Differential RNA processing of a common primary transcript determines whether the secreted or membrane form of an immunoglobulin will be produced.* Membrane bound or secreted form of immunoglobulin differs in the amino acid sequence of the heavy chain carboxyl terminal domains.

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