A patient presented with episodes of flushing and hypotension. His urinary 5HIAA levels were found to be increased. The diagnosis is
High-Yield Explanation
(B) Carcinoid syndrome # Carcinoid syndrome-Clinical findings include:> Flushing of the skin> Diarrhea and abdominal cramps> Right sided heart disease> Bronchoconstriction> Abdominal pain due to desmoplastic reaction of the mesentery in most patients, increased urinary excretion of 5-HIAA (5-hydroxy-indoleacetic acid), a degradation product of serotonin> Serotonin causes fibrosis of the tricuspid valve and pulmonary valve> "TIPS" - Tricuspid Insufficiency, Pulmonic Stenosis (fibrosis of tricuspid and pulmonary valves)