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General Medicine General 6db45b59

Which of the following is not true regarding super-antigens -

A

Bind T cells irrespective of antigen specificity of TCR

B

Bind directly to both MHC II and T cell receptor causing T cell activation

C

Bind to cleft (or antigen binding groov(e) in the MHC II molecule

D

Binds directly to lateral aspect of T cell receptor

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