Major change occurring in blood vessels in hypertension -a) Atherosclerosisb) Hyaline arteriosclerosisc) Multiple small aneurysmsd) Fibrinoid necrosis
High-Yield Explanation
Vascular pathology in Hypertension
Hypertension is associated with two forms of small blood vessels disease -
1. Hyaline arteriolosclerosis
There is homogenous, pink, hyaline thickening of arteriolar wall.
The lumen becomes narrow.
It is characteristic of benign hypertension.
It may also occur in diabetes and aging.
2. Hyperplastic arteriosclerosis
It is characteristic of malignant hypertension.
There is concentrentic, laminated thickening of arteriolar wall → onion skinning.
There is mutinous intimal thickening and fibrous intimal thickening.
There may be accompanied fibrinoid deposits with necrosis of the vessels wall → fibrinoid necrosis.