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Medicine General 6d03614c

Most unlikely cause of acute tubular necrosis amongst the following is :

A
Severe-bacterial-infection
B
Massive burn
C
Severe crush injury in the foot
D
Rupture of aoic aneurysm
High-Yield Explanation
Answer is D (Rupture of Aoic Aneurysm): Rupture of Aoic Aneurysm is the most unlikely cause of ATN amongst the following. It would rather result in instant death. Causes of Acute Tubular Necrosis Ischemic HvpovolemiuQ Low cardiac outputQ Renal vascular occlusionQ Renal vasoconstriction, DIC, Thrombotic microangiopathy (HUS, TTP, Malignant Hypeension, Vasculitis) Toxins Endogenous Toxins Rhabdomvolv.sis or Crush Syndrome (myoglobins)Q Hemolysis (hemoglobins)Q Uric acid, OxalateQ Plasma cell dyscrasias (Paraproteinemias e.g. myeloma)Q Massive burnsQ Exogenous Toxins Rudiocontrast agents Q CyclasporineQ Antibiotics (e.g. Aminoglycosides, Amphoterein B)Q Chemotherapy (eg. Cisplatin)Q Organic Solvents (e.g. Ethylene Glvcol)Q ParacetamolQ Illegal Aboifacients

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