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Pathology Neoplasia 6cd60c32

Mucosal melanosis and hamartomatous polyps are seen in?

A
Peutz-Jeghers syndrome
B
Cronkhite Canada syndrome
C
Familial adenomatous polyposis
D
Hereditary non polyposis colonic cancer
High-Yield Explanation
Ref: Harrison 19th ed., P 240* Peutz-Jeghers syndrome is characterized by dark brown spots on lips, buccal mucosa, nose and around eyes. There is concomitant intestinal polyposis. The most common location of polyps is in jejunum.* It is an autosomal dominant disorder with STK11 mutation.* The malignant potential of polyps ranges from never to rare transformation.

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