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Pathology Nephrotic Syndrome 6cd09c09

An IV drug abuser develops an aggressive form of nephrotic syndrome that does not respond to steroids. A renal biopsy is performed. Which of the following histological diagnoses will most likely be made from the biopsy tissue?

A
Focal segmental glomerulosclerosis
B
IgA nephropathy
C
Membranous glomerulonephritis
D
Membranoproliferative glomerulonephritis
High-Yield Explanation
Focal segmental glomerulosclerosis Associated with IV drug abuse and HIV nephropathy. Aggressive form of nephrotic syndrome Poor prognosis Non responsive to steroid therapy (called as 'collapsing variant').

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