Which of the following is the earliest change in intestine which occurs in Crohn’s disease?
High-Yield Explanation
Ref. Robbins Pathology. 9th edition. Page. 800
Crohns Disease
Present with skip lesions
Earliest lesion – Aphthous ulcers
Can involve whole of GIT – Form oral cavity to amus
Smoking is a risk factor
Fissure, fistula seen
Stricture seen
Gross features – Creeping pad of fat, Cobblestone appearance
Microscopy - Non caseating granuloma under microscopy, Transmural inflammation