Major amino acid released from muscle during starvation

Glucose-Alanine cycle (Cahill cycle) is transpoed to liver, transaminated to pyruvate and conveed to glucose. This glucose may again enter the glycolytic pathway to form pyruvate, which in turn, can be transaminated to alanine. -alanine cycle is impoant in conditions of starvation (Fig. 9.30). Thus net transfer of amino acid (nitrogen) from muscle to liver and corresponding transfer of glucose (energy) from liver to muscle is affected. cycle is intimately related with Cori&;s cycleRef: DM Vasudevan, 7th edition, page no: 120