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Pharmacology General 6bd6f323

Thromboxane A2 synthetase inhibition is by -

A
Aspirin
B
Prednisolone
C
Dazoxiben
D
Naproxen
High-Yield Explanation
Ans. is 'c' i.e., Dazoxiben o All the given drugs can inhibit Thromboxane A synthesis but only Dazoxiben can inhibit Thromboxane A 2synthetase. Note : According to KDT, aspirin also inhibits TX-synthatase also, but no other book (Goodman & Gilman, Katzung, Laurence, Satoskar) has mentioned this. Also know : Daltroban and sultroban are TXA2 receptor antagonists.

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