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Pharmacology Anti Adrenergic System 6bbd139e

Antiglaucoma drug which acts by increasing uveo- sclerol outflow -

A
Apraclonidine
B
Latanoprost
C
Timolol
D
Brinzolamide
High-Yield Explanation
Ans. is 'b' i.e., Latanoprost Drugs used in open-angle glaucoma MechanismMethods of AdministrationCholinomimetics Pilocarpine, carbachol, physostigmine, echothiophate, demecariumCiliary muscle contraction, opening of trabecular meshwork, increased outflowTopical drops of gel; plastic film slow-release insertAlpha agonists UnselectiveEpinephrine, dipivefrinIncreased outflowTopical dropsAlpha2-selectiveDecreased aqueous secretion ApraclonidineBrimonidine Topical, postlaser only TopicalBeta-blockers Timolol, betaxolol, carteolol, levobunolol, metipranololDecreased aqueous secretion from the ciliary epitheliumTopical dropsDiuretics Dorzolamide, brinzolamideDecreased aqueous secretion due to lack of HCO3TopicalAcetazolamide, dichlorphenamide, Methazolamide OralProstaglandins Lantanoprost, bimatoprost, travoprost, unoprostoneIncreased outflowTopical

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