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Medicine All India exam 6aeb5316

The following feature is common to both cytotoxic T cells and NK cells?

A
Synthesizes antibodies
B
Require antibodies to be present for action
C
Effective against virus infected cells
D
Recognize antigen in association with HLA class II markers
High-Yield Explanation
Common to both cytotoxic T cells and NK cells is affectivity against virus-infected cellsNK cells:1st line of defense against virus-laden cells and neoplastic cellsCytotoxicity is not MHC restricted Cytotoxic T cells:They are antigen-specific T cells whose function is to produce antigen-specific lysis of target cells by the direct cell to cell contactAre usually CD+ class I MHC restricted T cellsAre impoant in defense against virus infections of tissues (Ref: Harrison's 18/e p2688,2669)

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