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Pharmacology General 6ac214c5

Statin having longest half life: September 2012

A
Rosuvastatin
B
Pravastatin
C
Simvastatin
D
Lovastatin
High-Yield Explanation
Ans. A i.e. Rosuvastatin Rosuvastatin It is a competitive inhibitor of the enzyme HMG-CoA reductase, having a mechanism of action similar to that of other statins. Its approximate elimination half life is 19 h and its time to peak plasma concentration is reached in 3-5 h following oral administration.

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