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Pharmacology JIPMER 2017 6aa77f9e

All the following drugs are used in the treatment of metastatic breast cancer except:

A
Ixabepilone
B
Abemaciclib
C
Ribociclib
D
Sunitinib
High-Yield Explanation
Sunitinib is a novel oral multitargeted tyrosine kinase inhibitor with antitumor and antiangiogenic activities. It was recently approved in first-line treatment for patients with advanced renal cell carcinoma (RCC) and for the treatment of patients with gastrointestinal stromal tumors (GIST). Ixabepilone: Antimicrotubule inhibitor(M Phase) : use for breast cancer Abemaciclib and Ribocilib: CDK-4 and CDK-6 inhibitor use in breast cancer

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