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Pharmacology Endocrinology 6a988479

Drugs of the choice for central diabetes insipidus is

A
Desmopressin
B
Leuprolide
C
Thiazide diuretics
D
Insulin
High-Yield Explanation
*Desmopressin is treatment of choice for central diabetes insipidus. *It acts selectively at V2 receptors to increase urine concentration and decrease urine flow in a dosedependent Manner. *It is also more resistant to degradation than AVP and has a three- to fourfold longer duration of action. *Desmopressin can be given by IV or SC injection,nasal inhalation,or oral tablet.

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