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Pharmacology Chemotherapy 6a42ee4e

All cause myelosuppression except:

A
Docetaxel
B
Vincristine
C
Methotrexate
D
Irinotecan
High-Yield Explanation
Vincristine ( oncovin): It is a rapidly acting drug, very useful for inducing remission in childhood acute leukaemia, but is not good for maintenance therapy. Other indications are lymphosarcoma, Hodgkin&;s disease, Wilms&; tumour, Ewing&;s sarcoma and carcinoma lung. Prominent adverse effects are peripheral neuropathy and alopecia. Bone marrow depression is minimal. ESSENTIALS OF MEDICAL PHARMACOLOGY K.D.TRIPATHI SIXTH EDITION PAGE NO:825

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