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Gynaecology & Obstetrics Contraceptives 6a35d6ec

You are evaluating the laboratory results of a patient on oral contraceptive pills. Use of the birth control pill decreases which of the following?

A
Glucose tolerance
B
Binding globulins
C
High-density lipoprotein (HDL) cholesterol
D
Triglycerides
High-Yield Explanation
Combination-type oral contraceptives are potent systemic steroids that may cause many detectable alterations in metabolic function, such as increases in binding globulins, bromsulphalein retention, triglycerides and total phospholipids, and a decrease in glucose tolerance. Thus, the benefits of birth control pills must be weighed carefully against the added risks in patients with diabetes, cardiovascular disease, or liver disease. The pill modestly increases HDL cholesterol levels, but should have no direct effect on hemoglobin concentration. In fact, since bleeding volume is generally diminished in birth control pill users, hemoglobin concentration often increases in these patients.

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