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Social & Preventive Medicine General 69d83e6c

An agricultural labourer presented with progressive spastic paralysis is diagnosed of having neurolathyrism. It results from consumption of:

A
Aflatoxin
B
BOAA
C
Pyruvic acid
D
Sanguinarine
High-Yield Explanation
Lathyrism results due to ingestion of chick peas (Lathyrus sativus) containing the excitotoxin beta-N-oxalylamino-l-alanine (BOAA). Lathyrus sativus is commonly known as 'Khesari dhal'. Lathyrism is a neurologic syndrome characterized by the relatively acute onset of pain, paresthesia, and weakness in the lower extremities, progressing to a permanent spastic paraplegia. Diets containing over 30% of this dhal if taken over a period of 2-6 months will result in neurolathyrism. Ref: Textbook of Preventive and Social Medicine by K Park, 19th edition, Page 512.

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