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Pharmacology General 69b79edd

Low doses of aspirin used in myocardial infarction act by -

A
Inhibiting thromboxane synthetase
B
Inhibit cyclooxygenase
C
Releasing EDRF
D
High protein binding activity
High-Yield Explanation
Ans. is 'b' i.e., Inhibit cyclooxygenase Aspirin (in low doses) ---> inhibits synthesis of TXA2 by inhibiting the enzyme cycloxygenase So that immediate precursor (prostaglandins) of TXA2 are not synthesized. o Ticlopidine, clopidogrel -4 they block ADP mediated cAMP inactivation.

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